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. 2022 Mar 29;98(13):e1304–e1314. doi: 10.1212/WNL.0000000000200017

Figure 5. Cortical Proteins Are Multifunctional, May Provide Resilience for Aging Phenotypes, and Are Associated With AD Pathologic Phenotypes.

Figure 5

(A) Many of the cortical proteins included in the cognitive resilience index are also associated with Alzheimer disease (AD) pathologic phenotypes, including a summary score for AD pathology, β-amyloid, and tau tangles. (B) Venn diagram illustrates that most of the 52 cognitive resilience proteins are also associated with AD pathologic phenotypes. ADRD = AD and related dementia; SRM = selective reactive monitoring.