Table 4.
The main clinical and demographic characteristics of Groups A, B, and C.
| Group A (%) | Group B (%) | Group C (%) | p | |
|---|---|---|---|---|
| n. | 580 | 100 | 252 | |
| Age (years) | 44.6 ± 11.4 | 49.0 ± 12.0 | 47.3 ± 10.1 | <0.0001 |
| Gender (M/F) | 365 (62.9)/215 (37.1) | 69 (69)/31 (31) | 161 (63.9)/91 (36.1) | 0.5 |
| Dialysis (HD/PD) | 523 (90.1)/57 (9.9) | 95 (95)/5 (5) | 232 (92.1)/20 (7.9) | 0.2 |
| Dialysis vintage (years) | 5.8 ± 4.3 | 7.0 ± 4.5 | 6.8 ± 4.5 | 0.01 |
| HCV+ (n,%) | 76, 13.1 | 24, 24.0 | 56, 22.2 | 0.0006 |
| Body mass index (BMI) (kg/m2) | 23.8 ± 3.8 | 24.8 ± 3.8 | 24.2 ± 3.6 | 0.03 |
| Panel reactive antibodies (%) | 7.1 ± 4.3 | 7.3 ± 4.4 | 7.0 ± 5.1 | 0.9 |
| Cold ischemia time (hours) | 13.2 ± 5.0 | 10.6 ± 3.2 | 13.1 ± 5.4 | <0.0001 |
| Mismatches (n) | 3.1 ± 0.9 | 3.0 ± 0.8 | 3.4 ± 0.9 | <0.0001 |
| Donor age (years) | 42.3 ± 17.3 | 53.0 ± 15.9 | 48.5 ± 16.9 | <0.0001 |
| Donor serum creatinine (mg/dl) | 1.18 ± 0.61 | 1.69 ± 1.16 | 1.37 ± 0.84 | 0.002 |
| Cause of death (trauma/vascular) | 211 (36.4)/304 (63.6) | 24 (24)/66 (66) | 81 (32.1)/150 (67.9) | 0.02 |
| Cyclosporine (n) | 300 (51.7) | 93 (93) | 15 (5.9) | <0.0001 |
| Tacrolimus (n) | 262 (45.2) | 3 (3) | 214 (84.9) | <0.0001 |
| mTOR inhibitors (n) | 74 (3.1) | 4 (4) | 2 (0.8) | <0.0001 |