Table 2.
The association of SETDB1 expression and clinical characteristics in MM samples from GSE24080.
| Characteristics | Total | High expression | Low expression | p value |
|---|---|---|---|---|
| Sex | ||||
| Female | N = 554 | 117 | 103 | 0.224# |
| Male | 160 | 174 | ||
| ISOTYPE | ||||
| Light chain | N = 536 | 42 | 41 | <0.05# |
| IgA | 80 | 52 | ||
| IgG | 144 | 167 | ||
| Other | 2 | 8 | ||
| MRI (numbers of magnetic resonance imaging (MRI)-defined focal lesions spine) pelvis)) | ||||
| ≥ 3 | N = 517 | 148 | 153 | 0.694# |
| <3 | 110 | 106 | ||
| Cyto.Abn (An indicator of the detection of cytogenetic abnormalities) | ||||
| Yes | N = 554 | 114 | 90 | <0.05# |
| No | 163 | 187 | ||
| Age (years)(mean(range)) | N = 554 | 57.81 (29.7-75.94) | 56.61 (24.83-76.5) | 0.099† |
| β2M (mg/l)(mean(SD)) | N = 553 | 5.205 (5.8479) | 4.166 (4.6239) | <0.01† |
| CRP (mg/l)(mean(SD)) | N = 550 | 11.398 (21.5856) | 11.843 (24.5054) | 0.746 † |
| CREAT (mg/dl)(mean(SD) | N = 551 | 1.359 (1.3162) | 1.272 (1.2187) | 0.315† |
| LDH (U/l)(mean(SD)) | N = 554 | 177.69 (68.69) | 165.34 (61.346) | <0.05† |
| ALB (g/l)(mean(SD)) | N = 554 | 4.015 (0.6326) | 4.089 (0.5222) | 0.509† |
| HGB ((g/dl)(mean(SD)) | N = 554 | 11.070 (1.8093) | 11.445 (1.7988) | <0.05† |
| ASPC (%) (mean(SD)) | N = 526 | 43.858 (25.2960) | 41.235 (23.1060) | 0.274† |
| BMPC (%) (mean(SD)) | N = 539 | 49.390 (26.723) | 43.380 (25.5590) | <0.01† |