Table 2.
Patient Characteristics | Preemptive First Transplant, N=124,238 | Preemptive Second Transplant, N=16,186 | ||
---|---|---|---|---|
Odds Ratio (95% Confidence Interval) | P Value | Odds Ratio (95% Confidence Interval) | P Value | |
Employment | ||||
Full time | Reference | — | Reference | — |
Part time/full time | 0.82 (0.74 to 0.91) | <0.001 | 1.03 (0.78 to 1.38) | 0.82 |
Part time | 0.55 (0.51 to 0.58) | <0.001 | 0.64 (0.53 to 0.77) | <0.001 |
Unemployed | 0.37 (0.36 to 0.39) | <0.001 | 0.49 (0.44 to 0.55) | <0.001 |
Retired | 0.53 (0.50 to 0.56) | <0.001 | 0.74 (0.60 to 0.92) | 0.006 |
Education | ||||
None/grade school | Reference | — | Reference | — |
High school | 1.49 (1.35 to 1.64) | <0.001 | 1.01 (0.74 to 1.38) | 0.93 |
College/technical school | 1.73 (1.56 to 1.91) | <0.001 | 1.06 (0.77 to 1.46) | 0.71 |
Bachelor degree | 2.08 (1.87 to 2.30) | <0.001 | 1.33 (0.97 to 1.83) | 0.08 |
Graduate school | 2.65 (2.38 to 2.95) | <0.001 | 1.60 (1.14 to 2.25) | 0.007 |
Women | 1.45 (1.40 to 1.50) | <0.001 | 1.42 (1.29 to 1.57) | <0.001 |
Race | ||||
White | Reference | — | Reference | — |
Black | 0.37 (0.36 to 0.39) | <0.001 | 0.61 (0.52 to 0.70) | <0.001 |
Hispanic | 0.50 (0.47 to 0.52) | <0.001 | 0.63 (0.52 to 0.75) | <0.001 |
Other | 0.48 (0.44 to 0.51) | <0.001 | 0.74 (0.58 to 0.95) | 0.02 |
Comorbidities | ||||
Coronary artery disease | 0.69 (0.64 to 0.73) | <0.001 | 0.60 (0.49 to 0.74) | <0.001 |
Hypertension | 0.89 (0.86 to 0.94) | <0.001 | 1.14 (0.99 to 1.31) | 0.07 |
Peripheral vascular disease | 0.78 (0.71 to 0.84) | <0.001 | 1.11 (0.88 to 1.40) | 0.38 |
Diabetes | 0.76 (0.73 to 0.79) | <0.001 | 1.17 (1.04 to 1.32) | 0.008 |
Body mass index, kg/m2 | ||||
<18.5 | Reference | — | Reference | — |
18.5 to <25 | 1.16 (1.04 to 1.29) | 0.009 | 1.25 (0.97 to 1.60) | 0.08 |
25 to <30 | 1.24 (1.12 to 1.39) | <0.001 | 1.25 (0.97 to 1.61) | 0.09 |
30 to <35 | 1.21 (1.08 to 1.35) | 0.001 | 1.45 (1.11 to 1.90) | 0.006 |
≥35 | 1.03 (0.91 to 1.16) | 0.63 | 1.11 (0.81 to 1.52) | 0.51 |
PRA | ||||
<20 | Reference | — | Reference | — |
20–80 | 1.04 (0.98 to 1.10) | 0.21 | 0.48 (0.43 to 0.54) | <0.001 |
≥80 | 0.98 (0.88 to 1.10) | 0.75 | 0.29 (0.25 to 0.34) | <0.001 |
Live donor | 3.83 (3.70 to 3.96) | <0.001 | 2.65 (2.40 to 2.93) | <0.001 |
Age, yr | ||||
<40 | Reference | — | Reference | — |
40–60 | 1.33 (1.28 to 1.39) | <0.001 | 1.25 (1.12 to 1.39) | <0.001 |
≥60 | 1.66 (1.57 to 1.76) | <0.001 | 1.41 (1.18 to 1.68) | <0.001 |
ABO | ||||
O | Reference | — | Reference | — |
A | 1.19 (1.15 to 1.23) | <0.001 | 1.18 (1.06 to 1.30) | 0.002 |
B | 1.06 (1.00 to 1.11) | 0.04 | 1.05 (0.89 to 1.24) | 0.58 |
AB | 1.53 (1.41 to 1.65) | <0.001 | 1.68 (1.36 to 2.07) | <0.001 |
—, no data; PRA, panel reactive antibody.