Table 3.
Association of the presence of depressive symptoms at baseline with time to start of dialysis, all-cause mortality and a combined adverse outcome
| Entire cohort | Men | Women | ||||
|---|---|---|---|---|---|---|
| Outcome | Crude HR (95% CI) | Adjusted HRa (95% CI) | Crude HR (95% CI) | Adjusted HRa (95% CI) | Crude HR (95% CI) | Adjusted HRa (95% CI) |
| (N = 1326) | (N = 1326) | (N = 883) | (N = 883) | (N = 443) | (N = 443) | |
| Start of dialysis | 1.03 (0.84–1.27) | 1.05 (0.84–1.31) | 1.15 (0.90–1.47) | 1.08 (0.83–1.40) | 1.05 (0.70–1.56) | 1.19 (0.75–1.88) |
| All-cause mortality | 1.38 (1.08–1.75)** | 1.26 (0.98–1.63) | 1.59 (1.19–2.14)** | 1.41 (1.03–1.93)* | 1.15 (0.76–1.75) | 1.01 (0.64–1.58) |
| Combined adverse outcomeb | 1.16 (0.96–1.36) | 1.15 (0.97–1.36) | 1.31 (1.08 –1.58)** | 1.20 (0.98–1.47) | 1.09 (0.82–1.46) | 1.10 (0.80–1.51) |
The HR (95% CI) indicates the increased rate of an event (start of dialysis, all-cause mortality and combined adverse outcome) for the presence of depressive symptoms at baseline (i.e. a score ≤70 on the mental health score).
aAdjusted for age, sex, ethnicity, level of education, PKD, CCI, BMI, smoking status, SGA, eGFR at baseline, and plasma albumin and urea levels.
bCombined adverse outcome: either start of dialysis or all-cause mortality.
*P < 0.05, **P < 0.01.