Table 3.
Prevalence of symptoms at baseline, by sex
| Symptoms | Overall | Women | Men | P-value |
|---|---|---|---|---|
| Constipation | 33.5 | 41.9 | 28.8 | <0.001 |
| Decreased appetite | 29.3 | 34.2 | 26.6 | 0.03 |
| Muscle cramps | 57.1 | 59.5 | 55.8 | 0.35 |
| Swelling in legs | 56.5 | 63.7 | 52.4 | 0.003 |
| Shortness of breath | 46.8 | 52.5 | 43.6 | 0.02 |
| Dizziness | 37 | 40.8 | 34.8 | 0.11 |
| Restless legs | 32.3 | 41.5 | 27.2 | <0.001 |
| Tingling in feet | 34.5 | 40.5 | 31.1 | 0.01 |
| Fatigue | 76.2 | 79.9 | 74.2 | 0.082 |
| Cough | 38.6 | 38.7 | 38.6 | 0.99 |
| Dry mouth | 55.8 | 62.3 | 52.3 | 0.01 |
| Bone or joint pain | 58.6 | 69.0 | 52.8 | <0.001 |
| Headache | 25.7 | 34.9 | 20.5 | <0.001 |
| Muscle soreness | 35.6 | 42.6 | 31.7 | 0.003 |
| Dry skin | 57.9 | 69.4 | 51.5 | <0.001 |
| Itching | 54.6 | 55.6 | 54.0 | 0.71 |
| Trouble falling asleep | 40.3 | 49.3 | 35.2 | <0.001 |
| Trouble staying asleep | 54.1 | 61.6 | 49.9 | 0.002 |
| Decreased interest in sex | 58.9 | 50.7 | 63.4 | 0.001 |
| Difficulty becoming sexually aroused | 57.9 | 45.4 | 64.8 | <0.001 |
| Loss of strength | 64.3 | 67.6 | 62.4 | 0.17 |
Significant differences between women and men are in bold.