Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutational landscape. Cases of MDS/MPN-U with isolated i(17q) shows significantly higher frequency of mutations in SETBP1 and SRSF2 compared to cases of MDS/MPN-U without i(17q). There were no significant differences in mutational frequencies in other genes such as ASXL1 and TET2. TP53 mutations were rare. Cases of MDS/MPN-U with clonal mutations in one of the MPN-associated genes that included JAK2, CALR and MPL were excluded.
