FIG. 5.

Schematic representation of EMB resistance-associated amino acid replacements identified in the EmbCAB proteins, modeled by the method described by Sonnhammer et al. (30). (A) EmbC; (B), EmbA; (C), EmbB. The single-letter amino acid (aa) designations used are A (alanine), C (cysteine), D (aspartic acid), F (phenylalanine), G (glycine), H (histidine), I (isoleucine), K (lysine), L (leucine), M (methionine), N (asparagine), P (proline), Q (glutamine), R (arginine), S (serine), T (threonine), V (valine), and Y (tyrosine).