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. 2022 Mar 30;12:5398. doi: 10.1038/s41598-022-09348-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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T2 relaxation time values in the Nucleus pulposus (NP) of ovine intervertebral discs according to the modified Boos’ score and the Pfirrmann grade. The mean T2 relaxation time of the NP was measured by regions-of-interest (ROIs) that included the NP or a part of the NP of each lumbar ovine disc on the sagittal T2-weighted image and by copying this ROI onto the corresponding T2 mapping image. Equal-oblong ROIs delimitated (a) the junction between the NP and the ventral Annulus fibrosus (AF) (T2 ROI 2), (b) the NP (T2 ROI 3), and (c) the junction between the NP and the dorsal AF (T2 ROI 4). (d) A manually drawn oval delineated the NP (T2 ROI B). The modified Boos’ scoring was negatively correlated with the NP values measured for ROIs 2, 3, 4, and B on the T2 mapping images (p < 0.001).