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Anti-tumor mechanism of nIT in patients with MSI-H/dMMR CRC. nIT, Neoadjuvant immunotherapy; MSI-H, Microsatellite instability-high; dMMR, Deficient mismatch repair; CRC, Colorectal cancer; TMB, Tumor mutation burden; TNB, Tumor neo-antigen; ORR, Objective response rate; pCR, Pathological complete response.
