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. 2022 Mar 17;9:727487. doi: 10.3389/fcvm.2022.727487

Table 1.

Impact of commonly used antihypertensive drugs on cancer risk.

Antihypertensive drugs Effects on various cancers
Diuretics Increase the risk of breast and skin cancer; may increase the incidence of urinary cancer
CCBsa Increase the incidence of skin cancer and urinary system cancer
β2 receptor blocker Reduce the incidence of lung cancer and digestive system tumors, and have different conclusions on the effects of head and neck squamous cell carcinoma, breast cancer, skin cancer and urinary system tumors.
ACEI/ARBb Reduce the incidence of breast cancer, urinary tract cancer, and digestive tract cancer May increase the incidence of lung cancer, especially after using high dose ACEI (56).
a

CCBs, Calcium channel blockers;

b

ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin-receptor antagonists.