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. 2022 Mar 28;28(12):1204–1219. doi: 10.3748/wjg.v28.i12.1204

Table 1.

Gut microbiota functions

Bacterial phylum
Key representatives
Functions
Firmicutes Members of the genera Enterococcus, Ruminococcus, Clostridium, Lactobacillus, Faecalibacterium, Roseburia, and Eubacterium Metabolism of amino acids[23,24], carbohydrates[25], bile acids, and their salts[22]. Lipid metabolism and cholesterol synthesis[25]. Synthesis of vitamins К2, B1, B2, B6, B7, B9, and B12[26]. Maintenance of a proper immune response[28,29] and intestinal epithelial barrier integrity[31,32]. Protection against enteric pathogens[33]
Bacteroidetes Members of the genera Bacteroides and Prevotella Metabolism of amino acids[24], carbohydrates[25,141], bile acids, and their salts[22,142]. Synthesis of vitamin К2[27]. Regulation of appetite[143]. Maintenance of a proper immune response[28-29] and intestinal epithelial barrier integrity[31]. Protection against enteric pathogens[33]
Actinobacteria Members of the genera Bifidobacterium and Corynebacterium Metabolism of bile acids and their salts[22]. Synthesis of vitamins К2, B1, B2, B6, B7, B9, and B12[26]. Protection against enteric pathogens[33]
Proteobacteria Members of the genera Desulfovibrio, Escherichia, and Shigella Metabolism of amino acids[144]