Table 1.
World Health Organization classification of gastroenteropancreatic neuroendocrine neoplasms
|
Grade 1 NET
|
Grade 2 NET
|
Grade 3 NET
|
Grade 3 NEC
|
|||||
|
Mitoses/10 hpf
|
Ki-67
|
Mitoses/10 hpf
|
Ki-67
|
Mitoses/10 hpf
|
Ki-67
|
Mitoses/10 hpf
|
Ki-67
|
|
| 2010 | < 2 | < 3% | 2-20 | 3%-20% | - | - | > 20 | > 20% |
| 20171 | < 2 | < 3% | 2-20 | 3%-20% | > 20 | > 20% | > 20 | > 20% |
| 2019 | < 2 | < 3% | 2-20 | 3%-20% | > 20 | > 20% | > 20 | > 20% |
1
Pancreas only.
NET: Neuroendocrine tumor; NEC: Neuroendocrine carcinoma; hpf: High power field.