Table 2.
Proportions of individuals receiving at least one prescription for antipsychotics during follow-up
| Total | Prescribed antipsychotics, n (%) | Recorded SMI | Prescribed antipsychotics, n (%) | No recorded SMI | Prescribed antipsychotics, n (%) | ||||
| All | 46 210 | 15 562 | (33.7) | 9335 | 6354 | (68.1) | 36 875 | 9208 | (25.0) |
| Gender | |||||||||
| Men | 22 682 | 6958 | (30.7) | 4689 | 3044 | (64.9) | 17 993 | 3914 | (21.8) |
| Women | 23 528 | 8604 | (36.6) | 4646 | 3310 | (71.2) | 18 882 | 5294 | (28.0) |
| Age, years | |||||||||
| 0–15 | 384 | 26 | (6.8) | 6 | 4 | (66.7) | 378 | 22 | (5.8) |
| 15–19 | 1729 | 556 | (32.2) | 179 | 127 | (70.9) | 1550 | 429 | (27.7) |
| 20–24 | 4482 | 1543 | (34.4) | 707 | 450 | (63.6) | 3775 | 1093 | (29.0) |
| 25–29 | 5089 | 1866 | (36.7) | 1004 | 665 | (66.2) | 4085 | 1201 | (29.4) |
| 30–34 | 5312 | 2009 | (37.8) | 1178 | 835 | (70.9) | 4134 | 1174 | (28.4) |
| 35–39 | 5541 | 2068 | (37.3) | 1291 | 905 | (70.1) | 4250 | 1163 | (27.4) |
| 40–44 | 5251 | 1924 | (36.6) | 1214 | 840 | (69.2) | 4037 | 1084 | (26.9) |
| 45–49 | 4379 | 1503 | (34.3) | 1002 | 718 | (71.7) | 3377 | 785 | (23.2) |
| 50–54 | 3802 | 1169 | (30.7) | 783 | 524 | (66.9) | 3019 | 645 | (21.4) |
| 55–59 | 3053 | 816 | (26.7) | 596 | 421 | (70.6) | 2457 | 395 | (16.1) |
| 60–64 | 2335 | 586 | (25.1) | 469 | 308 | (65.7) | 1866 | 278 | (14.9) |
| 65–69 | 1657 | 420 | (25.3) | 311 | 190 | (61.1) | 1346 | 230 | (17.1) |
| 70–74 | 1152 | 337 | (29.3) | 214 | 128 | (59.8) | 938 | 209 | (22.3) |
| 75–100 | 2044 | 739 | (36.2) | 381 | 239 | (62.7) | 1663 | 500 | (30.1) |
| Townsend deprivation score | |||||||||
| 1 (least deprived) | 5523 | 1486 | (26.9) | 893 | 592 | (66.3) | 4630 | 894 | (19.3) |
| 2 | 6700 | 1932 | (28.8) | 1144 | 772 | (67.5) | 5556 | 1160 | (20.9) |
| 3 | 9047 | 2956 | (32.7) | 1762 | 1204 | (68.3) | 7285 | 1752 | (24.0) |
| 4 | 11 654 | 4176 | (35.8) | 2563 | 1751 | (68.3) | 9091 | 2425 | (26.7) |
| 5 (most deprived) | 11 928 | 4559 | (38.2) | 2693 | 1861 | (69.1) | 9235 | 2698 | (29.2) |
| Missing | 1358 | 453 | (33.4) | 280 | 174 | (62.1) | 1078 | 279 | (25.9) |
| ICD-10 diagnostic category of PD | |||||||||
| Paranoid | 1988 | 1026 | (51.6) | 981 | 693 | (70.6) | 1007 | 333 | (33.1) |
| Schizoid | 1346 | 536 | (39.8) | 565 | 394 | (69.7) | 781 | 142 | (18.2) |
| Dissocial | 2407 | 763 | (31.7) | 536 | 337 | (62.9) | 1871 | 426 | (22.8) |
| Emotionally unstable | 12 300 | 5573 | (45.3) | 2591 | 1850 | (71.4) | 9709 | 3723 | (38.3) |
| Histrionic | 1168 | 285 | (24.4) | 178 | 116 | (65.2) | 990 | 169 | (17.1) |
| Anankastic | 3648 | 700 | (19.2) | 347 | 223 | (64.3) | 3301 | 477 | (14.5) |
| Anxious | 501 | 130 | (25.9) | 62 | 42 | (67.7) | 439 | 88 | (20.0) |
| Dependent | 2705 | 686 | (25.4) | 411 | 303 | (73.7) | 2294 | 383 | (16.7) |
| Other | 20 147 | 5863 | (29.1) | 3664 | 2396 | (65.4) | 16 483 | 3467 | (21.0) |
| Psychiatric comorbidity | |||||||||
| Any SMI | 9335 | 6354 | (68.1) | 9335 | 6354 | (68.1) | 0 | 0 | (.) |
| Schizophrenia | 4105 | 2981 | (72.6) | 4105 | 2981 | (72.6) | 0 | 0 | (.) |
| Bipolar disorder | 2987 | 2044 | (68.4) | 2987 | 2044 | (68.4) | 0 | 0 | (.) |
| Other psychotic illness | 5071 | 3583 | (70.7) | 5071 | 3583 | (70.7) | 0 | 0 | (.) |
| Post-traumatic stress disorder | 1468 | 731 | (49.8) | 306 | 223 | (72.9) | 1162 | 508 | (43.7) |
| Eating disorder | 2852 | 1233 | (43.2) | 613 | 448 | (73.1) | 2239 | 785 | (35.1) |
| Depression | 34 522 | 12 698 | (36.8) | 7116 | 4979 | (70.0) | 27 406 | 7719 | (28.2) |
| Anxiety | 23 595 | 9201 | (39.0) | 5006 | 3601 | (71.9) | 18 589 | 5600 | (30.1) |
| Phobia | 3279 | 1272 | (38.8) | 666 | 470 | (70.6) | 2613 | 802 | (30.7) |
| Hypochondria | 416 | 176 | (42.3) | 117 | 81 | (69.2) | 299 | 95 | (31.8) |
| Obsessive–compulsive disorder | 5333 | 1517 | (28.4) | 831 | 560 | (67.4) | 4502 | 957 | (21.3) |
| Other neurosis | 1353 | 466 | (34.4) | 332 | 245 | (73.8) | 1021 | 221 | (21.6) |
| No recorded psychiatric comorbidity | 5763 | 874 | (15.2) | 0 | 0 | (.) | 5763 | 874 | (15.2) |
| Recorded adverse childhood experiences | |||||||||
| No record | 41 468 | 13 798 | (33.3) | 8389 | 5774 | (68.8) | 33 079 | 8024 | (24.3) |
| Record | 4742 | 1764 | (37.2) | 946 | 580 | (61.3) | 3796 | 1184 | (31.2) |
ICD-10, International Classification of Diseases-10th revision; PD, personality disorder; SMI, severe mental illness.