Table 1. Patient Characteristics and Outcomes of All Lung Cancer, Adenocarcinoma, and SCLC Cases From 2011 to 2018a.
| Factor | No. (%) | ||
|---|---|---|---|
| All lung cancer (N = 83 590) | Adenocarcinoma (n = 56 511) | SCLC (n = 6338) | |
| Age, y | |||
| <70 | 47 505 (56.8) | 35 229 (62.3) | 3267 (51.5) |
| ≥70 | 36 085 (43.2) | 21 282 (37.7) | 3071 (48.5) |
| Sex | |||
| Female | 34 896 (41.7) | 30 039 (53.2) | 655 (10.3) |
| Male | 48 694 (58.3) | 26 472 (46.8) | 5683 (89.7) |
| Smoking status | |||
| Never-smokers | 42 158 (50.4) | 35 668 (63.1) | 858 (13.5) |
| Smokers | 35 598 (42.6) | 17 904 (31.7) | 5000 (78.9) |
| Unknown | 5834 (7.0) | 2939 (5.2) | 480 (7.6) |
| ECOG PS | |||
| 0-1 | 45 133 (54.0) | 32 956 (58.3) | 3011 (47.5) |
| ≥2 | 13 943 (16.7) | 8054 (14.3) | 1562 (24.6) |
| Unknown | 24 514 (29.3) | 15 501 (27.4) | 1765 (27.8) |
| Stage | |||
| I-III | 33 424 (40.0) | 22 275 (39.4) | 1707 (26.9) |
| IV | 50 166 (60.0) | 34 236 (60.6) | 4631 (73.1) |
| Treatment | |||
| No | 12 126 (14.5) | 5055 (9.0) | 1261 (19.9) |
| Yes (any) | 71 464 (85.5) | 51 456 (91.1) | 5077 (80.1) |
| Outcome | |||
| 5-y OS rate, % | 26.0 | 33.0 | 4.8 |
| Median survival time (95% CI), mob | 18.2 (18.0-18.5) | 27.9 (27.4-28.3) | 7.2 (7.0-7.5) |
Abbreviations: ECOG PS, Eastern Cooperative Oncology Group performance status; HR, hazard ratio; OS, overall survival; SCLC, small cell lung carcinoma.
a
Comparison was conducted between lung adenocarcinoma and SCLC (patient characteristics by χ2 test and survival time by log-rank test and Cox proportional hazards regression model). All differences were significant at P < .001.
b
Adenocarcinoma vs SCLC: adjusted HR, 0.32 (95% CI, 0.31-0.33).