TABLE 3.

Aqueous solubility prediction of erianin and reference drugs.

Compounds	Solubility	Solubility level
Erianin	−4.221	2 (yes, low)
Carboplatin	−0.553	4 (yes, optimal)
Gemcitabine	−0.844	4 (yes, optimal)
Gefitinib	−5.561	2 (yes, low)
Erlotinib	−5.11	2 (yes, low)
Anlotinib	−6.31	1 (no, very low, but possible)
Osimertinib	−5.694	2 (yes, low)
Pemetrexed	−3.488	3 (yes, good)
TAX (Taxol)	−3.515	3 (yes, good)
Cis-platinum	−1.479	4 (yes, optimal)
Navelbine	−6.805	1 (no, very low, but possible)