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. 2022 Mar 17;9:862932. doi: 10.3389/fmolb.2022.862932

TABLE 6.

Hepatotoxicity prediction of erianin and reference drugs.

Compounds Hepatotoxic Prediction Applicability #MD Applicability #Mdpvalue
Erianin 0.244421 TRUE 8.92613 4.94E-01
Carboplatin −3.70565 TRUE 5.69559 0.999998
Gemcitabine −2.15171 TRUE 8.43163 7.35E-01
Gefitinib −3.99306 TRUE 14.2139 2.99E-09
Erlotinib −2.16035 TRUE 13.3441 3.25E-07
Anlotinib −1.78405 TRUE 13.0744 1.26E-06
Osimertinib 2.59551 TRUE 15.515 1.21E-12
Pemetrexed 1.63974 TRUE 12.5966 1.22E-05
TAX (Taxol) −9.53069 FALSE 16.426 3.21E-15
Cis-platinum −6.17439 FALSE 10.0087 8.84E-02
Navelbine −4.69006 FALSE 16.5462 1.43E-15