Table 2. General Medical Conditions: Disorders Within Each Category and Their Frequencies (N = 5 946 800).
| Category | Coding definition | Diagnosis codes (ICD-10) | Medication | Frequency in study population, No. (%) | |
|---|---|---|---|---|---|
| Drug codes (ATC) | Time frame for prescriptions | ||||
| Circulatory system | 2 091 874 (35.18) | ||||
| Hypertension | Diagnosis and/or prescription for antihypertensive drugsa | I10-I13, I15 | C02, C03, C04, C07, C08, C09 | Twice in 1 y | 1 715 324 (28.84) |
| Dyslipidemia | Diagnosis and/or prescription for lipid-lowering drugsb | E78 | C10 | Twice in 1 y | 718 252 (12.08) |
| Ischemic heart disease | Diagnosis and/or prescription for antianginal drug | I20-I25 | C01DA | Twice in 1 y | 496 179 (8.34) |
| Atrial fibrillation | Diagnosis | I48 | 317 756 (5.34) | ||
| Heart failure | Diagnosis | I50 | 226 584 (3.81) | ||
| Peripheral artery occlusive disease | Diagnosis | I70-I74 | 200 967 (3.38) | ||
| Stroke | Diagnosis | I60-I64, I69 | 323 376 (5.44) | ||
| Endocrine system | 701 207 (11.79) | ||||
| Diabetes | Diagnosis and/or prescription for antidiabetic drugs | E10-E14 | A10A, A10B | Twice in 1 y | 389 474 (6.55) |
| Thyroid disorder | Diagnosis and/or prescription for thyroid therapy | E00-E05, E061-E069, E07 | H03 | Twice in 1 y | 325 962 (5.48) |
| Gout | Diagnosis | E79, M10 | 45 891 (0.77) | ||
| Pulmonary system and allergy | 2 065 927 (34.74) | ||||
| Chronic pulmonary disease | Diagnosis and/or prescription for obstructive airway disease drugs | J40-J47 | R03 | Twice in 1 y | 1 320 124 (22.20) |
| Allergy | Diagnosis and/or prescription for nonsedative antihistamines and/or nasal antiallergic drugs | J30.1-J30.4, L23, L50.0, T78.0. T78.2, T78.4 | R06AX, R06AE07, R06AE09, R01AC, R01AD | Twice in 1 y | 1 178 428 (19.82) |
| Gastrointestinal system | 405 284 (6.82) | ||||
| Ulcer/chronic gastritis | Diagnosis | K221, K25-K28, K293-K295 | 168 968 (2.84) | ||
| Chronic liver disease | Diagnosis | B16-B19, K70, K74, K766, I85 | 55 708 (0.94) | ||
| Inflammatory bowel disease | Diagnosis | K50-K51 | 66 059 (1.11) | ||
| Diverticular disease of intestine | Diagnosis | K57 | 153 531 (2.58) | ||
| Urogenital system | 338 356 (5.69) | ||||
| Chronic kidney disease | Diagnosis | N03, N11, N18-N19 | 95 761 (1.61) | ||
| Prostate disorders | Diagnosis and/or prescription for prostate hyperplasia therapy | N40 | C02CA, G04C | Twice in 1 y | 264 827 (4.45) |
| Musculoskeletal system | 395 245 (6.65) | ||||
| Connective tissue disorders | Diagnosis | M05-M06, M08-M09, M30-M36, D86 | 154 935 (2.61) | ||
| Osteoporosis | Diagnosis and/or prescription for osteoporosis drugs | M80-M82 | M05B, G03XC01, H05AA | Twice in 1 y | 280 383 (4.71) |
| Painful conditions | Repeated prescriptions of analgesics | N02A, N02BA51, N02BE, M01A, M02A | 4× in 1 y | 1 833 828 (30.84) | |
| Hematological system | 242 914 (4.08) | ||||
| HIV/AIDS | Diagnosis | B20-B24 | 4142 (0.07) | ||
| Anemias | Diagnosis | D50-D53, D55-D59, D60-D61, D63-D64 | 239 140 (4.02) | ||
| Cancers | Diagnosis | C00-C43, C45-C97 | 549 081 (9.23) | ||
| Neurological system | 1 244 857 (20.93) | ||||
| Vision problems | Diagnosis | H40, H25, H54 | 448 885 (7.55) | ||
| Hearing problems | Diagnosis | H90-H91, H931 | 422 046 (7.10) | ||
| Migraine | Diagnosis and/or prescription for specific antimigraine drugs | G43 | N02C | Twice in 1 y | 252 834 (4.25) |
| Epilepsy | Diagnosis and prescription for antiepileptic drugs | G40-G41 | N03 | Twice in 1 y | 77 826 (1.31) |
| Parkinson disease | Diagnosis | G20-G22 | 27 458 (0.46) | ||
| Multiple sclerosis | Diagnosis | G35 | 18 757 (0.32) | ||
| Neuropathies | Diagnosis | G50-G64 | 269 995 (4.54) | ||
Abbreviations: ATC, Anatomical Therapeutic Chemical; ICD-10, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision.
a
Ascertained solely by prescriptions only in absence of ischemic heart disease or heart failure and by diuretics only if no kidney disease.
b
Prescriptions used if no previous ischemic heart disease.