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. Author manuscript; available in PMC: 2022 Mar 31.
Published in final edited form as: J Med Chem. 2021 Apr 6;64(8):4913–4946. doi: 10.1021/acs.jmedchem.1c00019

Figure 4.

Figure 4.

Pharmacokinetic parameters and conc vs. time profiles in brain and plasma of CD1 mice (n=3) after a single of 30 mpk oral dose of (+)-119 formulated as a solution in 20% PEG300, 40% of Solutol® solution (30% w/w in water), and 40% DI water.