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. 2022 Mar 17;10:853757. doi: 10.3389/fpubh.2022.853757

Table 5.

Performance summary of the supervised machine learning models with the highest Youden's index.

Models with the
best Youden index
VRE (503/3860 = 13.03%) Models with the
best Youden index
MRSA (332/4446 = 7.47%)
Log. Reg. XGBoost Rand. Forest Log. Reg. XGBoost Rand. Forest
Training AUC 0.76 0.77 0.77 Training AUC 0.65 0.66 0.66
Testing AUC 0.80 0.77 0.77 Testing AUC 0.66 0.66 0.70
Testing sensitivity 0.80 0.73 0.75 Testing sensitivity 0.70 0.67 0.76
Testing specificity 0.66 0.65 0.66 Testing specificity 0.55 0.60 0.59
Youden index 0.46 0.39 0.41 Youden index 0.24 0.27 0.34
Threshold opt. bound 0.15 0.15 0.20 Threshold opt. bound 0.20 0.10 0.30
Models with the
best Youden index
CRE (53/3661 = 1.45%) Models with the
best Youden index
MDRO (792/4503 = 17.59%)
Log. Reg. XGBoost Rand. Forest Log. Reg. XGBoost Rand. Forest Dec. Tree
Training AUC 0.70 0.76 0.79 Training AUC 0.72 0.86 0.87 0.76
Testing AUC 0.78 0.72 0.72 Testing AUC 0.70 0.87 0.89 0.81
Testing sensitivity 0.73 0.73 0.64 Testing sensitivity 0.56 0.75 0.82 0.89
Testing specificity 0.73 0.77 0.79 Testing specificity 0.75 0.82 0.83 0.65
Youden index 0.45 0.50 0.42 Youden index 0.30 0.57 0.65 0.54
Threshold opt. bound 0.025 0.015 0.05 Threshold opt. bound 0.50 0.30 0.40 0.30