Table 4.
Effect modification by gender on association between overdose risk and having reported using a kit – Adjusted odds ratios and 99% confidence intervals for odds of having reported using a kit vs not having reported using a kit, stratified by gender
| Variable | Unstratified (N = 189,178) | Gender: Male (N = 99,738) | Gender: Female (N = 86,633) | Gender: OtherA (N = 2,807) | ||||
|---|---|---|---|---|---|---|---|---|
| AOR* (99% CI) | p-value | AOR (99% CI) | p-value | AOR (99% CI) | p-value | AOR (99% CI) | p-value | |
| Risk of Overdose | ||||||||
| Not at Risk | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| At Risk | 6.82 (6.57 – 7.09) | < 0.001 | 5.37 (5.08 – 5.67) | < 0.001 | 8.35 (7.90 – 8.82) | < 0.001 | 3.68 (2.82 – 4.79) | < 0.001 |
| Year | ||||||||
| 2017 | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| 2018 | 1.59 (1.53 – 1.66) | < 0.001 | 1.59 (1.50 – 1.68) | < 0.001 | 1.63 (1.52 – 1.74) | < 0.001 | 1.25 (0.79 – 1.97) | 0.206 |
| 2019 | 1.85 (1.77 – 1.93) | < 0.001 | 1.85 (1.75 – 1.96) | < 0.001 | 1.87 (1.75 – 2.00) | < 0.001 | 1.17 (0.72 – 1.90) | 0.396 |
| 2020 | 2.76 (2.65 – 2.88) | < 0.001 | 2.77 (2.63 – 2.93) | < 0.001 | 2.83 (2.65 – 3.02) | < 0.001 | 2.20 (1.41 – 3.43) | < 0.001 |
| Health Region | ||||||||
| Fraser | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| Interior | 1.35 (1.30 – 1.40) | < 0.001 | 1.46 (1.39 – 1.53) | < 0.001 | 1.27 (1.20 – 1.34) | < 0.001 | 0.50 (0.35 – 0.72) | < 0.001 |
| Island | 1.35 (1.30 – 1.40) | < 0.001 | 1.49 (1.42 – 1.56) | < 0.001 | 1.20 (1.14 – 1.27) | < 0.001 | 1.11 (0.81 – 1.53) | 0.388 |
| Northern | 0.70 (0.67 – 0.74) | < 0.001 | 0.74 (0.69 – 0.79) | < 0.001 | 0.66 (0.61 – 0.71) | < 0.001 | 1.06 (0.61 – 1.84) | 0.792 |
| Vancouver Coastal | 0.99 (0.95 – 1.04) | 0.664 | 1.07 (1.01 – 1.14) | 0.001 | 0.91 (0.85 – 0.97) | < 0.001 | 0.76 (0.53 – 1.10) | 0.059 |
| Age Group | ||||||||
| Under 19 | 1.00 | - | 1.00 | - | 1.00 | - | 1.00 | - |
| 19—30 | 1.94 (1.81 – 2.07) | < 0.001 | 1.84 (1.67 – 2.03) | < 0.001 | 2.05 (1.86 – 2.25) | < 0.001 | 1.87 (1.21 – 2.89) | < 0.001 |
| 31—60 | 2.19 (2.05 – 2.34) | < 0.001 | 2.14 (1.95 – 2.35) | < 0.001 | 2.24 (2.04 – 2.46) | < 0.001 | 1.83 (1.20 – 2.80) | < 0.001 |
| Over 60 | 1.35 (1.22 – 1.49) | < 0.001 | 1.36 (1.18 – 1.56) | < 0.001 | 1.29 (1.10 – 1.52) | < 0.001 | 1.35 (0.66 – 2.77) | 0.276 |
Abbreviations: AOR adjusted odds ratio
* Odds ratio between each group and the reference group for each variable, after adjusting for all other variables: overdose risk, year, health region, age group