Table 7.
Association between in-hospital mortality and the acute kidney injury stages in diagnosed by Creatinine kinetics, “Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease”, Acute Kidney Injury Network, and Kidney Disease Improving Global Outcomes
Variables
|
Univariable analysis
|
Multivariable analysis
|
|||
Odds ratio (95%CI)
|
P
value
|
Odds ratio (95%CI)
|
P
value
|
||
KDIGO | Stage 1 | 1.64 (1.11-2.41) | 0.013 | 0.70 (0.27-1.83) | 0.635 |
Stage 2 | 2.51 (1.33-4.71) | 0.004 | 0.15 (0.00-4.76) | 0.242 | |
Stage 3 | 5.65 (2.92-10.93) | < 0.001 | 0.10 (0.00-7.83) | 0.705 | |
RIFLE | Stage 1 | 1.86 (1.16, 2.96) | 0.010 | 0.97 (0.39-2.43) | 0.879 |
Stage 2 | 2.70 (1.48-4.90) | 0.001 | 3.26 (0.18-59.43) | 0.166 | |
Stage 3 | 6.14 (3.08-12.25) | < 0.001 | 1.90 (0.07-49.94) | 0.466 | |
AKIN | Stage 1 | 1.77 (1.21-2.59) | 0.004 | 1.32 (0.39-4.40) | 0.933 |
Stage 2 | 2.54 (1.32-4.88) | 0.005 | 3.23 (0.33-31.98) | 0.552 | |
Stage 3 | 6.25 (3.13-12.49) | < 0.001 | 16.88 (0.74-349.18) | 0.403 | |
CK | Stage 1 | 1.49 (0.89-2.51) | 0.132 | 1.34 (0.44-4.83) | 0.500 |
Stage 2 | 2.49 (1.32-4.70) | 0.005 | 1.07 (0.35-3.25) | 0.579 | |
Stage 3 | 4.40 (2.20-8.79) | < 0.001 | 0.72 (0.17-2.98) | 0.615 |
ORs are adjusted for ethnicity, age, sex, Elixhauser score, simplified acute physiology score, SOFA, Glasgow Coma Scale, craniotomy, max creatinine, creatinine at admission, use of antiplatelet drugs, anticoagulant, vancomycin, angiotensin receptor blocker/angiotensin-converting enzyme inhibitor and aminoglycosides, transfusion, red blood cell, plasma and shock. P values < 0.05 were considered statistically significant. KDIGO: Kidney Disease Improving Global Outcomes; AKIN: Acute Kidney Injury Network; RIFLE: Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease; CK: Creatinine kinetics; CI: Confidence interval.