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. 2022 Mar 8;38(3):208–215. doi: 10.1089/aid.2021.0091

Table 5.

Multivariate Model of Type 2 Diabetes Mellitus Incidence (Defined by Incident Antihyperglycemic Medication Prescription at 18 Months Postinitiation) by Integrase Strand Transfer Inhibitor Versus Nonintegrase Strand Transfer Inhibitor

Factor HR Standard error 95% CI p
InSTI use (vs. non-InSTI) 1.30 0.76 −0.19 to 2.80 0.73
ART initiation year 2010–2012 0.77 0.93 −1.04 to 2.59 0.78
ART initiation year 2012–2014 1.44 0.79 −0.11 to 2.98 0.65
ART initiation year 2014–2016 1.25 0.97 −0.65 to 3.15 0.82
ART initiation year 2016–2018 2.66 1.14 0.43 to 4.88 0.39
Age at ART initiation 1.03 0.02 0.99 to 1.07 0.19
Sex: female 2.72 0.54 1.66 to 3.78 0.06
Race: white 0.58 0.78 −0.96 to 2.11 0.48
Ethnicity: Hispanic or Latinx 1.42 0.62 0.21 to 2.63 0.57
NRTI backbone: TAF 1.60 1.03 −0.42 to 3.62 0.65
NRTI backbone: ABC 2.67 0.72 1.26 to 4.08 0.17
NRTI backbone: other 0.00 4,795.79 −9,399.73 to 9,399.74 1.00
CD4 at ART initiation 1.00 0.01 1.00 to 1.00 0.20
HIV-1 RNA viral load at ART initiation 1.00 0.00 1.00 to 1.00 0.456

ABC, abacavir; TAF, tenofovir alafenamide.