Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 17;9:799053. doi: 10.3389/fnut.2022.799053

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Qiao, Wang, Wang, Han, Qi, Zhang, Liu and You.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

AOM/1.5% DSS induced CAC in mice. (A) Body weights of mice in the AOM/1.5% DSS group (n = 10 biologically independent animals per group). AOM (10 mg/kg) was intraperitoneally injected into 8-week-old mice on day 1, and 1.5% DSS was administered via the drinking water on day 5 for 5 d. (B) The numbers of colon tumors in BD5115 and SM group mice (n = 10 biologically independent BD5115 animals vs. n = 10 SM animals; ** P < 0.01, Student's t-test). (C) Macroscopic observation of the colon tissues of mice in the BD5115 group and SM group. The bar represents 1 cm. (D) GO analysis of differentially expressed genes in the distal colons of mice in the BD5115 group and SM group (n = 3 biologically independent BD5115 animals vs. n = 3 SM animals). (E) Heatmap of 53 CAC-related genes. (F) Survival curve analysis of the MAFF gene in the TCGA database.