Table 3.
Association of FCGRIA variant haplotypes (rs1848781-rs587598788-rs1050204) with sarcoidosis susceptibility.
| Haplotypers1848781-rs587598788-rs1050204 | Estimated Frequency (%) | Logistic regression | Logistic regression adjusted for sex and age | |||
|---|---|---|---|---|---|---|
| Case (N = 670) | Control (N = 669) | P value* | OR (95% CI) | P value* | OR (95% CI) | |
| C-In-G | 74.7% | 71.6% | ||||
| G-In-A | 12.7% | 11.5% | 0.261 | 0.877 (0.698-1.102) | 0.267 | 0.876 (0.693-1.107) |
| G-In-G | 8.9% | 9.0% | 0.827 | 0.973 (0.758-1.247) | 0.826 | 0.969 (0.735-1.278) |
| C-Del-A | 2.3% | 4.2% | 0.008 | 0.542 (0.346-0.849) | 0.008 | 0.543 (0.346-0.853) |
| C-Del-G | 1.9% | 2.4% | 0.306 | 0.765 (0.458-1.277) | 0.313 | 0.762 (0.450-1.292) |
*The p-values for the estimated haplotype were generated using the most common haplotyoe rs1848781C-rs587598788In-rs1050204G as the reference for the logistic regression analyses.