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. 2022 Mar 17;13:831397. doi: 10.3389/fgene.2022.831397

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Copyright © 2022 Lv, Fang, Qi, Xu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Let-7c-5p is poorly expressed in LUAD cells, hinders LUAD cell proliferation, and can alleviate the capacity of HOXA11-AS on proliferating the LUAD cells. (A,B) Let-7c-5p expression in LUAD tissue and adjacent normal tissue. (C) Expression of let-7c-5p in normal cell line HBE4-E6/E7 and LUAD cell lines A549 evaluated in qRT-PCR assay. (D) let-7c-5p expression in each transfection group measured by performing qRT-PCR. (E) CCK-8 was applied to test the viability of cells. (F) Ki67 expression was measured by Western blot; *p < 0.05.