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. 2022 Mar 17;13:831397. doi: 10.3389/fgene.2022.831397

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Copyright © 2022 Lv, Fang, Qi, Xu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HOXA11-AS facilitates LUAD cell growth in vivo via mediating the let-7c-5p/IGF2BP1 axis in mice. (A) Tumor condition in the HOXA11-AS inhibited group and the control group. (B) Growth curve of the tumors in mice. (C) Weight of the tumors was recorded. (D) qRT-PCR assay was conducted to assess the expression of HOXA11-AS, let-7c-5p, and IGF2BP1 in tumor tissue of mice. (E) By performing immunohistochemical analysis, expression of Ki67 and IGF2BP1 was determined (×400); *p < 0.05.