TABLE 1.
Parameter | PS | DHEAS |
---|---|---|
τdesensitization at 30 µM (s) (control in same cells) |
4.1 ± 0.4 (41 ± 12) |
2.3 ± 0.8 (43 ± 12) |
IC50,peak (µM) | 0.26 ± 0.03 | 1.01 ± 0.12 |
nH,peak | −0.73 ± 0.05 | −0.81 ± 0.06 |
IC50,sustained (µM) | 1.45 ± 0.26 | 11.4 ± 0.8 |
nH,sustained | −0.90 ± 0.11 | −1.51 ± 0.10 |
K (µM) | 22.6 ± 3.6 | 336 ± 25 |
e | 6.2 × 10−5 ± 3.3 × 10−5 | 6.2 × 10-5* |
*Constrained as described in Results. The numbers of cells are provided in text.