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. 2022 Mar 30;80:101. doi: 10.1186/s13690-022-00813-6

Table 10.

Ovarian Cancer – Spatially and Temporally Lagged Space-Time Regression

Lagged Variables Parameter Model
Parameter Estimate (C.I.) P Coefficient Value P-Value
Comprehensive Interactive Model - 1 Spatial Lag
spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races)
Spatial Lags: White 47.91 (20.68, 75.13) 0.0006 S.D. 0.4125
THC, 1 Age −2 (−3.46, − 0.55) 0.0070 Log.Lik −672.3628
Cannabidiol, 1 Cannabigerol: Cannabidiol − 0.94 (− 1.59, − 0.28) 0.0053 phi 4.2682 1.83e-08
Cannabigerol, 1 THC: Cannabigerol −6.3 (− 10.51, − 2.08) 0.0034 rho − 0.5883 2.59e-12
THC −31.25 (−46.22, − 16.28) 4.3e-05 lambda 0.6520 < 2.2e-16
Spatial: Comprehensive Interactive Model - 1 Spatial & 1 Temporal Lags
THC, 1 THC Lagged both Temporally and Spatially
Cannabigerol, 1 spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races)
Cannabidiol, 1 Cigarettes 6.17 (3.38, 8.97) 1.54e-05 S.D. 0.6109
Temporal: Hispanic 0.16 (0.03, 0.29) 0.0162 Log.Lik −621.5385
Cigarettes,1 African −0.11 (−0.21, − 0.02) 0.0201 phi 0.5509 8.38e-05
AUD,1 AIAN −5.2 (−8.47, −1.94) 0.0018 rho −0.6617 9.76e-16
THC, 1 Cigarettes: CBG: CBD −0.28 (− 0.45, − 0.11) 0.0013 lambda 0.6109 <  2.2e-16
Analgesics, 1 Income −0.83 (−1.3, − 0.36) 0.0006
Cocaine, 1 THC −0.22 (− 0.32, − 0.12) 1.07e-05
Spatial: Comprehensive Interactive Model - 1 Spatial & 2 Temporal Lags
THC, 1 THC Lagged both Temporally and Spatially
Cannabigerol, 1 spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races)
Cannabidiol, 1 CBG 0.77 (0.38, 1.16) 9.90e-05 S.D. 0.6190
Temporal: Income −0.76 (−1.23, − 0.29) 0.0017 Log.Lik −567.1623
Cigarettes,2 THC −0.52 (− 0.78, − 0.26) 7.78e-05 phi 0.5898 8.16e-05
AUD,2 THC −0.33 (− 0.48, − 0.17) 2.67e-05 rho −0.5512 2.44e-08
THC, 2 lambda 0.5790 <  2.2e-16
Analgesics, 2
Cocaine, 2
Spatial: Comprehensive Interactive Model - 1 Spatial & 4 Temporal Lags
THC, 1 THC Lagged both Temporally and Spatially
Cannabigerol, 1 spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races)
Cannabidiol, 1 CBG 0.76 (0.22, 1.31) 0.0061 S.D. 0.5875
Temporal: Cocaine 0.25 (0.09, 0.42) 0.0023 Log.Lik − 452.9861
Cigarettes,4 THC: CBG 0.2 (0.05, 0.35) 0.0073 phi 0.4665 0.0001169
AUD,4 Cigarettes: THC: CBG: THC −4.21 (−8.39, −0.03) 0.0482 rho −0.4140 0.0006749
THC, 4 Cigarettes: THC: CBG: CBD: THC −1.24 (−2.34, −0.15) 0.0261 lambda 0.4449 7.33e-08
Analgesics, 4 THC −0.47 (− 0.62, − 0.33) 9.73e-11
Cocaine, 4