Table 2.
Prostatic Cancer – Lagged Space – Time Models
| Lagged Variables | Parameter | Model | ||||
|---|---|---|---|---|---|---|
| Parameter | estimate (C.I.) | P | Coefficient | Value | P-Value | |
| LAGGING WITH CANNABINOIDS | ||||||
| Comprehensive Interactive Model - 2 Temporal Lags | ||||||
| spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races) | ||||||
| Temporal Lags: | Cocaine | 80.28 (15.7, 144.86) | 0.0148 | S.D. | 5.2086 | |
| THC, 2 | CBD | 5.95 (0.76, 11.15) | 0.0247 | Log.Lik | − 1772.068 | |
| Cannabidiol, 2 | Analgesics | 59.62 (6.42, 112.81) | 0.0280 | phi | 2.689466 | 0.0004161 |
| Cannabigerol, 2 | Income | 3.89 (0.36, 7.43) | 0.0308 | psi | 0.583621 | < 2.2e-16 |
| CBG | −5.07 (−9.71, − 0.44) | 0.0318 | rho | − 0.826646 | < 2.2e-16 | |
| Cigarettes: CBG | −62.38 (−108.32, −16.43) | 0.0078 | lambda | 0.84905 | < 2.2e-16 | |
| Cigarettes | − 282.27 (− 484.13, −80.41) | 0.0061 | ||||
| Cigarettes: CBD | −88.44 (−137.35, −39.53) | 0.0004 | ||||
| Cigarettes: CBG: CBD | −20.64 (− 31.36, −9.92) | 0.0002 | ||||
| Age | −0.72 (−1.09, − 0.35) | 0.0001 | ||||
| Comprehensive Interactive Model - 4 Temporal Lags | ||||||
| spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races) | ||||||
| Temporal Lags: | Cocaine | 0.0006 | 0.0006 | S.D. | 4.7498 | |
| THC, 4 | Hispanic | 0.0012 | 0.0012 | Log.Lik | − 1505.899 | |
| Cannabidiol, 4 | Age | 2.18e-10 | 2.18e-10 | phi | 2.091523 | 0.0004814 |
| Cannabigerol, 4 | psi | 0.652059 | < 2.2e-16 | |||
| rho | −0.829187 | < 2.2e-16 | ||||
| lambda | 0.876342 | < 2.2e-16 | ||||
| Comprehensive Interactive Model - 6 Temporal Lags | ||||||
| spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races) | ||||||
| Temporal Lags: | Cigarettes: THC: CBG | 24.04 (14.72, 33.36) | 4.29e-07 | S.D. | 5.1497 | |
| THC, 6 | Cigarettes: CBG | 334.94 (176.94, 492.95) | 3.26e-05 | Log.Lik | − 1218.3530 | |
| Cannabidiol, 6 | Cigarettes | 1080.16 (552.4, 1607.92) | 6.03e-05 | phi | 2.710614 | 3.11e-05 |
| Cannabigerol, 6 | Cigarettes: CBG: CBD | 49.06 (17.39, 80.73) | 0.0024 | psi | 0.617539 | < 2.2e-16 |
| Cigarettes: CBD | 150.69 (45.25, 256.13) | 0.0051 | rho | −0.722522 | < 2.2e-16 | |
| Age | − 0.63 (−1.09, − 0.18) | 0.0067 | lambda | 0.822562 | < 2.2e-16 | |
| CBG | −38.43 (−55.72, −21.13) | 1.33e-05 | ||||
| THC | −53.27 (−77, −29.55) | 1.07e-05 | ||||
| THC: CBD | −20.22 (− 28, − 12.44) | 3.49e-07 | ||||
| Comprehensive Interactive Model - 1 Spatial Lag | ||||||
| spreml(Cancer Rate ~ Age + Cigarettes * THC * CBG * CBD + AUD + Analgesics + Cocaine + Income + Five Races) | ||||||
| Spatial Lags: | Cigarettes: THC: CBD | −128.412 (− 202.52, − 54.31) | 0.0006 | S.D. | 5.1497 | |
| THC, 1 | Cigarettes: THC: CBG: CBD | −38.166 (− 59.63, − 16.7) | 0.0070 | Log.Lik | − 2081.4700 | |
| Cannabidiol, 1 | Cigarettes: THC | −517.602 (− 800.36, − 234.85) | 0.0053 | phi | 2.09673 | 3.96e-06 |
| Cannabigerol, 1 | Cigarettes: THC: CBG | −151.094 (− 232.66, −69.53) | 0.0034 | psi | 0.593689 | < 2.2e-16 |
| Age | − 0.949 (−1.34, − 0.56) | 4.3e-05 | rho | − 0.765839 | < 2.2e-16 | |
| lambda | 0.867413 | < 2.2e-16 | ||||