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. 2022 Mar 17;13:778221. doi: 10.3389/fphar.2022.778221

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Copyright © 2022 Yang, Geng, You, Yuan, Meng, Ma, Gu and Lei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemical analysis of p-JAK2 and p-STAT3 in pancreatic tissues. (A) Representative immunohistochemistry images of p-JAK2 and p-STAT3 in pancreatic tissues 24 h after the induction of SAP; Scale bar: 25 μm. (B) Positive cell ratio of pancreatic tissue sections. Data are expressed as mean ± SD (n = 3 per group). Significance between groups was evaluated by one way analysis of variance (ANOVA) followed by a Tukey post hoc test. *p < 0.05, **p < 0.01 and ***p < 0.001 compared with the SO group; ^# p < 0.05, ^## p < 0.01 and ^### p < 0.001 compared with the SAP group. JAK2, janus kinase two; STAT3, signal transducer and activator of transcription three; SO, sham operation; SAP, severe acute pancreatitis.