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. 2022 Mar 17;13:778221. doi: 10.3389/fphar.2022.778221

FIGURE 7.

FIGURE 7

AR42J cell injury model established by cerulein treatment. (A) The amylase activity was measured at different time points. (B,C) Western blot findings of p-JAK2, JAK2, p-STAT3 and STAT3 protein expression in AR42J cells treated with cerulein. (D) Peak of p-JAK2, JAK2, p-STAT3 and STAT3 proteins expression at different simultaneous phase sites. (E) amylase activity in the control, cerulein, rhein 0.25 μg/ml, rhein 0.5 μg/ml and rhein 1 μg/ml groups (F) The TNF-α levels in the control, cerulein, rhein 0.25 μg/ml, rhein 0.5 μg/ml and rhein 1 μg/ml groups. Data are expressed as mean ± SD (n = 5 per group). Significance between groups was evaluated by one way analysis of variance (ANOVA) followed by a Tukey post hoc test. JAK2, janus kinase two; STAT3, signal transducer and activator of transcription 3.