TABLE 4.

Univariable association with all-cause mortality.

	Systemic sclerosis patients (n = 100)
	Hazard ratio (95% CI)	p-value
Age (years)	1.02 (0.99−1.05)	0.189
Sex (male)	2.65 (1.15−6.08)	0.021
Diffuse systemic sclerosis	0.91 (0.41−2.03)	0.810
Age of diagnosis >60 years	1.44 (0.57−3.67)	0.454
Atrial fibrillation	4.02 (1.72−9.42)	0.001
FVC of predicted (%)	0.98 (0.97−1.00)	0.058
DLCO of predicted (%)	0.97 (0.94−1.00)	0.069
Pulmonary involvement	1.47 (0.62−3.48)	0.379
Known coronary artery disease	2.63 (0.96−7.23)	0.061
NYHA class > II	3.38 (1.45−7.86)	0.005
Estimated RV systolic pressure (mmHg)*	1.03 (1.00−1.06)	0.068
Baseline CMR parameters
LV end-diastolic volume-indexed (mL/m2)	1.00 (0.98−1.02)	0.966
LVEF (%)	0.97 (0.94−1.00)	0.075
RV end-diastolic volume-indexed (mL/m2)	1.00 (0.99−1.02)	0.742
RVEF (%)	0.99 (0.95−1.03)	0.531
RA maximum volume-indexed (mL)	1.02 (1.00−1.04)	0.031
RA EF (%)	0.97 (0.94−1.01)	0.130
Presence of LGE	3.42 (1.42−8.28)	0.006
Presence of non-ischemic LGE	3.59 (1.43−9.01)	0.007
Strain measurements
RV global longitudinal strain (%)	1.03 (0.98−1.09)	0.248
RA reservoir strain (%)	0.95 (0.91−0.99)	0.009
RA conduit strain (%)	0.93 (0.88−0.98)	0.008
RA booster strain (%)	1.01 (0.95−1.07)	0.799

CMR, cardiac magnetic resonance; DLCO, diffusing capacity of the lungs for carbon monoxide; EF, ejection fraction; FVC, forced vital capacity; LGE, late gadolinium enhancement; LV, left ventricular; RA, right atrial; RV, right ventricular. *Available in 86 patients. Significant p-values (p < 0.05) are indicated in bold.