TABLE 1.

Amino acid substitutions introduced in the EV-A71 S41 infectious clone.

Mutant	Protein	Position	Amino acid substitution	Nucleotide changes
VP2 I149K	VP2	149	Isoleucine to Lysine	ATA to AAG
3AV62M	3A	62	Valine to Methionine	GTG to ATG
3AT66A	3A	66	Threonine to Alanine	ACT to GCC
3CI79T	3C	79	Isoleucine to Threonine	ATT to ACC
3CM182E	3C	182	Methionine to Glutamic acid	ATG to GAG
3DC113H	3D	113	Cysteine to Histidine	TGC to CAC
3DA436T	3D	436	Alanine to Threonine	GCA to ACA