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. 2022 Mar 31;22:272. doi: 10.1186/s12884-022-04595-1

Table 2.

Univariate analysis of variables associated with moderate to severe anxiety symptoms among pregnant persons (N = 4,303)

ORa 95% CIb X2 p-value
Demographic Characteristics
Participant Race/Ethnicity 0.1153
  White, non-Hispanic Ref
  Black/African American 1.48 0.94, 2.35
  Hispanic/Latinx 1.25 0.93, 1.67
  Asian 1.11 0.73, 1.69
  Native American 3.64 1.09, 12.15
  Pacific Islander  < 0.001  < 0.001, > 999.999
Participant Age 0.0006
  18–30 Ref
  31–35 0.70 0.56, 0.87
  36–40 0.58 0.44, 0.77
  41 +  0.73 0.45, 1.18
Household Income  < 0.0001
   < $99,999 Ref
  $100,000–250,999 0.42 0.35, 0.52
  $251,000 +  0.47 0.35, 0.64
Highest level education completed  < 0.0001
  Professional degree Ref
  Master’s 1.56 1.12, 2.16
  College 1.72 1.24, 2.38
   < College 3.47 2.50, 4.83
Pre-pregnancy insurance  < 0.0001
  Private Insurance Ref
  Other (including Medi-Cal, Tricare, other) 1.98 1.57, 2.49
Partnership status  < 0.0001
  Married or Partnered Ref
  Unpartnered 2.54 1.84, 3.51
Employment status 0.0018
  Full-time Ref
  Other (part-time, homemaker, unemployed) 1.37 1.12, 1.66
Employed in health care 0.0027
  No 1.38 1.12, -1.71
  Yes Ref
Obstetric and Medical history
Previous live birth 0.1680
  Yes Ref
  No 1.19 0.93, 1.54
History of prior miscarriage 0.0143
  No Ref
  Yes 1.32 1.06, 1.65
Receipt of care through fertility clinic this pregnancy 0.0009
  Yes Ref
  No 1.46 1.17, 1.82
History of anxiety disorder prior to pregnancy  < 0.0001
  No Ref
  Yes 3.88 3.22, 4.67
History of depression prior to pregnancy  < 0.0001
  No Ref
  Yes 3.36 2.78, 4.06
COVID-19 specific characteristics
History of obtaining a SARS-CoV-2 test this pregnancy 0.4091
  No Ref
  Yes 1.08 0.90, 1.30
History of a positive SARS-CoV-2 test this pregnancy 0.6460
  No Ref
  Yes 1.08 0.78, 1.49
Household contact diagnosed with COVID-19 since pregnant 0.7371
  No Ref
  Yes 0.94 0.68, 1.32
Household contact deceased from COVID-19 since pregnant 0.0001
  No Ref
  Yes 5.73 2.36, 13.90
Job loss since onset of COVID-19 pandemic  < 0.0001
  No Ref
  Yes 2.77 2.14, 3.57
Reduced hours at work since onset of COVID-19 pandemic  < 0.0001
  No Ref
  Yes 1.70 1.34, 2.15
Inability to pay rent or mortgage since onset of COVID-19 pandemic  < 0.0001
  No Ref
  Yes 5.44 3.94, 7.47
Very or Extremely Worried about COVID-19  < 0.0001
  No Ref
  Yes 3.32 2.76, 4.00
Perceived stress over the past month  < 0.0001
  Low Ref
  Moderate-High 11.00 8.38, 14.45

aOR odds ratio

bCI confidence interval