Table 1.
Name | Meningococcal serogroup | Type | US licensed age range |
---|---|---|---|
Menactra (MenACWY-D) [10] | A, C, W, Y | Polysaccharides conjugated to diphtheria toxoid |
9 months − 55 years |
Menveo (MenACWY-CRM) [11] | A, C, W, Y | Polysaccharides conjugated to CRM197, a (nontoxic) mutant diphtheria toxin |
2 months– 55 years |
MenQuadfi (MenACYW-TT) [12] | A, C, W, Y | Polysaccharides conjugated to tetanus toxoid | ≥ 2 years |
Nimenrix (MenACWY-TT) [13] | A, C, W, Y | Polysaccharides conjugated to tetanus toxoid | ≥ 6 weeksa |
Bexsero (MenB-4C) [50] | B | Recombinant-derived outer membrane proteins NadA, NHBA, fHbp (subfamily B), plus PorA-containing outer membrane vesicles | 10 − 25 years |
Trumenba (MenB-FHbp) [51] | B | Recombinant-derived lipidated fHbp (subfamily A and B) | 10 − 25 years |
fHbp factor H binding protein, NadA neisserial adhesin A, NHBA neisserial heparin binding antigen
aNot currently licensed in the United States