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. Author manuscript; available in PMC: 2022 Aug 13.
Published in final edited form as: Clin Sci (Lond). 2021 Aug 13;135(15):1825–1843. doi: 10.1042/CS20201574

Figure 10. Proximal tubule-specific deletion of AT1a receptors attenuates glomerular and tubulointerstitial injury in Ang II-induced hypertension in adult male PT-Agtr1a−/− mice.

Figure 10.

Semi-quantitative data showing that genetic deletion of AT1 (AT1a) receptors selectively in the proximal tubules of the kidney prevents Ang II-induced glomerular (A) and tubulointerstitail injury (B) in male PT-Agtr1a−/− mice. *P<0.05 vs. WT control. +P<0.05 vs. Ang II-infused WT mice. n=8 for each group.