Figure 6. Comparisons of general glomerular histology as stained by HE and Eosin in male WT and PT-Agtr1a^−/− mice under control conditions and during Ang II-induced hypertension treated with or without AT₁ receptor blocker losartan.

(A) WT control mice. (B) WT mice with Ang II infusion. (C) WT mice with concurrent Ang II infusion and losartan treatment. (D) PT-Agtr1a^−/− control mice. (E) PT-Agtr1a^−/− mice with Ang II infusion. (F) PT-Agtr1a^−/− mice with concurrent Ang II infusion and losartan treatment. There were no differences found in the glomerular histology between male WT and PT-Agtr1a^−/− mice. G, glomerulus; PT, proximal tubule. Magnification: ×40.