Figure 8. Comparisons of general proximal tubule and interstitial histology as stained by HE and Eosin in male WT and PT-Agtr1a^−/− mice under control conditions and during Ang II-induced hypertension treated with or without losartan.

(A) WT control mice. (B) WT mice with Ang II infusion. (C) WT mice with concurrent Ang II infusion and losartan treatment. (D) PT-Agtr1a^−/− control mice. (E) PT-Agtr1a^−/− mice with Ang II infusion. (F) PT-Agtr1a^−/− mice with concurrent Ang II infusion and losartan treatment. There were no differences found in the proximal tubule and interstitial histology between male WT and PT-Agtr1a^−/− mice. Magnification: ×40.