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. 2022 Mar 17;13:862741. doi: 10.3389/fgene.2022.862741

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Copyright © 2022 Lu, Luo, Wang, Chen, Zhang, Li, Chen, Li and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The differences of tumor immune microenvironment between the low- and high-risk groups. (A) Gene set enrichment analysis of the top 10 pathways significantly enriched in the risk groups. (B) The immune cell bubble of risk groups. (C–E) The box plots of the comparison of StromalScore, ImmuneScore, and ESTIMATEScore, respectively, between low- and high-risk groups. (F, G) The ssGSEA scores of immune cells and immune functions in the risk groups. (H) The difference of common immune checkpoint expression in the risk groups. *p < 0.05, **p < 0.01, ***p < 0.001.