Figure 3. Three-stage hierarchical regression model.
To control for the influence of inter-regional Euclidean distance and similarity in grey matter profiles on our connectivity-variability associations, we built a three-stage node-wise hierarchical regression model on group-level data. Node-wise adjusted R2 scores were calculated for the baseline model. For model 1 and 2 adjusted R2 change scores are reported. (A) Baseline model. Euclidean distance between regions explained on average 22% of rsFC variance across all nodes. (B) Model 1. Adding morphometric similarity only accounted for an extra 4% of rsFC variance across all regions, over the baseline model. (C) Model 2. Introducing inter-regional MSSD (irsMSSD) explained an additional 27% of rsFC variance.