Table 1.
Clinical characteristics of individual patients with NASH for PRM analysis.
| Cirrhosis | Early HCC | Late HCC | |
|---|---|---|---|
| No. | 35 | 27 | 10 |
| Gender (M/F) | 11/24 | 15/12 | 4/6 |
| Age (yrs) | 58.6 (32-76) | 68.0 (47-91.2) | 67.8 (57-80.8) |
| Laboratory | |||
| AFP (ng/mL) | 3.7 (1.7-9.1) | 32.4 (2-336) | 10609.6 (12.9-37830) |
| TBili (mg/dL) | 1.0 (0.2-3.3) | 1.1 (0.2-3) | 1.6 (0.3-3) |
| INR | 1.1 (0.9-1.7) | 1.2 (0.9-2.5) | 1.1 (1.0-1.3) |
| Creatinine (mg/dL) | 1.0 (0.5-7.4) | 1.0 (0.5-2.5) | 0.8 (0.4-1.3) |
| Score | |||
| MELD | 8.9 (6-23) | 10 (6-21) | 9 (7-12) |
| CTP | 6 (5-8) | 8 (5-10) | 7 (5-10) |
| TNM stage % (I/II/III/IV) | NA | 100/0/0/0 | 0/0/40/60 |
| Ascites % | 25.7% | 40.7% | 20% |
| Encephalopathy % | 20% | 22.2% | 20% |
| AFP < 20 ng/mL | 35 (100%) | 23 (85.2%) | 2 (20%) |
| Tumor size (cm) | NA | 3.1 (1.3-6) | 11.2 (4.6-18.5) |
AFP, TBili, ALT, AST, INR, and creatinine values and MELD and CTP scores were provided by the UT Southwestern Medical Center. Values are presented as median with the interquartile range (IQR). AFP, alpha-fetoprotein; TBili, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; INR, international normalized ratio; MELD, Model for end stage liver disease; CTP, Child-Turcotte-Pugh.
N/A, Not Applicable.