Table 2.

Summary statistics and ANCOVA of AUC for the change from baseline in MAS-PF to the end of MP (BOCF, FAS).

	IncobotulinumtoxinA (N = 104)	Placebo (N = 104)
Mean AUC ± SD	−7.74 ± 7.01	−4.76 ± 5.84
LS mean AUC ± SE	−8.40 ± 0.661	−5.81 ± 0.713
LS mean AUC difference (incobotulinumtoxinA–placebo) ± SE	−2.59 ± 0.892
95% CI	−4.35; −0.83
p-value	0.0041

ANCOVA, analysis of covariance; AUC, area under the curve; BOCF, baseline observation carried forward; CI, confidence interval; FAS, full analysis set; LS, least squares; MAS-PF, Modified Ashworth Scale spasticity score for the plantar flexors; MP, main period; N, number of subjects in each group; SD, standard deviation; SE, standard error.