Fig. 9.

Amyloid levels in APP/PS1 mice treated with GFP or sFKN virus are unaltered. Anti-Aβ staining of rAAV-GFP (A) and rAAV-sFKN (B) -injected mice hippocampi. Congo red staining of rAAV-GFP (C) and rAAV-sFKN (D) -injected mice hippocampi. Percentage area positive staining for anti-Aβ (E) and Congo red staining (F). Scale = 200 μm. Abbreviations: Aβ, amyloid beta; AAV, adeno-associated virus serotype; FKN, fractalkine; GFP, green fluorescent protein; rAAV, recombinant AAV; sFKN, secreted FKN.