TABLE 1.

Initial consensus after online voting: consensus achieved for 42 items

RDoC	MADRS	HAM-D17	IDS-SR	HAM-A	PANSS
Negative valence systems	10. Suicidal thoughts	1. Depressed mood 10. Anxiety (psychic) 11. Anxiety (somatic)	5. Feeling sad 18. Thoughts of death or suicide	1. Anxious mood 3. Fears 6. Depressed mood	G2. Anxiety
Positive valence systems	8. Inability to feel	N/A	8. Response of your mood to good or desired events 21. Capacity for pleasure or enjoyment (excluding sex) 22. Interest in sex (interest, not activity)	N/A	N/A
Cognitive systems	6. Concentration difficulties	N/A	15. Concentration/decision making	5. Intellectual	P2. Conceptual disorganization P3. Hallucinatory behavior N5. Difficulty in abstract thinking N6. Lack of spontaneity and flow of conversation N7. Stereotyped thinking G9. Unusual thought content G10. Disoreintation G11. Poor attention
Social processes	N/A	N/A	N/A	N/A	N3. Poor rapport
Arousal/regulatory systems	4. Reduced sleep	4. Insomnia (early in the night) 5. Insomnia (middle of the night) 6. Insomnia (early hours of the morning)	1. Falling asleep 2. Sleep during the night 3. Waking up too early 4. Sleeping too much 9. Mood in relation to time of day 20. Energy level	4. Insomnia 9. Cardiovascular symptoms 13. Autonomic symptoms	N/A
Sensorimotor systems	N/A	N/A	23. Feeling slowed down	N/A	G5. Mannerisms and posturing G7. Motor retardation

HAM-A: Hamilton Anxiety Rating Scale; HAM-D17: 17-item Hamilton Depression Rating Scale; IDS-SR: Inventory of Depressive Symptomatology, Self-Report; MADRS: Montgomery-Asberg Depression Rating Scale; PANSS: Positive and Negative Syndrome Scale; RDoC: Research Domain Criteria; N/A: not applicable