Table 1.
Sample demographics
| HV (n = 23) | PSZ (n = 26) | t/X2 | p | |
|---|---|---|---|---|
| Age | 34.92 (10.80) | 39.61 (11.88) | −1.44 | 0.16 |
| Gender [F, M] | [9, 14] | [7, 19] | 0.83 | 0.36 |
| Race | ||||
| African American, Caucasian, other | [8,14,1] | [8,16,2] | 0.28 | 0.87 |
| Education level (years) | 15.39 (1.70) | 13.19 (2.50) | 3.55 | <0.01 |
| Maternal education level | 15.00 (2.86) | 13.62 (2.79) | 1.69 | 0.10 |
| Paternal education level | 13.70 (3.25) | 14.08 (3.01) | −0.42 | 0.67 |
| WASI-II IQ score | 114.04 (12.81) | 103.93 (13.00) | 2.75 | <0.01 |
| MATRICS domains* | ||||
| Processing speed | 52.71 (9.77) | 42.41 (9.43) | 3.52 | <0.01 |
| Attention/vigilance | 49.38 (9.63) | 46.59 (11.80) | 0.85 | 0.40 |
| Working memory | 50.67 (9.89) | 42.32 (11.03) | 2.61 | 0.01 |
| Verbal learning | 51.48 (8.84) | 43.23 (10.14) | 2.84 | <0.01 |
| Visual learning | 44.48 (11.70) | 42.59 (13.35) | 0.49 | 0.63 |
| Reasoning | 50.43 (9.57) | 49.14 (8.59) | 0.47 | 0.64 |
| Social cognition | 51.71 (8.98) | 41.05 (11.75) | 3.34 | <0.01 |
| Smoking status [yes, no] | [6, 17] | [13, 13] | 2.94 | 0.09 |
| Antipsychotic medication | ||||
| Total haloperidol | 11.70 (7.18) | |||
| Clinical ratings | ||||
| BPRS positive | 1.97 (1.02) | |||
| BPRS negative | 1.76 (.68) | |||
| BPRS disorganization | 1.18 (.31) | |||
| BPRS total | 32.58 (7.77) | |||
| SANS avolition | 1.86 (1.43) | |||
| SANS anhedonia | 2.44 (1.01) | |||
| SANS total | 23.92 (13.54) |
*
MATRICS data were available for 21/23 HV and 22/26 PSZ