TABLE 2.
Baseline characteristics between those who progressed from MCI and those who did not
Median (interquartile range) or number (%) | |||
---|---|---|---|
Demographic and clinical characteristics | Not converted to dementia in 1 year (n = 204) | Converted to dementia in 1 year (n = 46) | P‐value |
Age | 70.33 (13) | 75.50 (12) | <.001* |
Female | 124 (60.8%) | 36 (78.3%) | .028* |
Marital status | .878 | ||
Single | 28 (13.9%) | 6 (13.3%) | |
Married | 139 (69.2%) | 30 (66.7%) | |
Divorced or widowed | 34 (16.9%) | 9 (20%) | |
Educational years | .097 | ||
Uneducated to 6 years | 46 (27.4%) | 18 (45%) | |
7‐12 years | 33 (19.6%) | 6 (15%) | |
More than 12 years | 89 (53%) | 16 (40%) | |
Family history of NCD | 31 (78.5%) | 8 (25.8%) | 1 |
Only first‐degree relationship | 20 (17.7%) | 8 (25.8%) | .442 |
Substance (current or ever) | |||
Alcohol use | 21 (20.2%) | 3 (11.5%) | .404 |
Smoking | 19 (18.3%) | 3 (11.5%) | .563 |
Concerned problem | |||
Cognitive | 187 (91.7%) | 44 (95.7%) | .54 |
Non‐cognitive | 59 (28.9%) | 17 (37%) | .292 |
Underlying disease and comorbidities | |||
Diabetes mellitus | 56 (27.5%) | 16 (34.8%) | .368 |
Hypertension | 142 (69.6%) | 33 (71.7%) | .86 |
Hyperlipidemia | 150 (73.5%) | 33 (71.7%) | .854 |
Cardiovascular risk group or stroke | 43 (21.1%) | 11 (23.9%) | .693 |
Parkinson disease | 13 (6.4%) | 1 (2.2%) | .477 |
Vitamin D deficiency | 23 (11.3%) | 12 (26.1%) | .012* |
Psychiatric disorder | |||
Underlying; depressive disorders | 20 (9.8%) | 3 (6.5%) | .777 |
Comorbid Depression | 26 (12.7%) | 5 (10.9%) | .811 |
Medication–AChEI | 32 (15.7%) | 12 (26.1%) | .131 |
Abbreviations: AChEI, acetylcholinesterase inhibitor; MCI, mild cognitive impairment; NCDs, Neurocognitive disorders.
P value < .05 is considered as statistically significant.