Table 1.
Baseline characteristics of the maintenance dialysis population by vaccine exposure
| Characteristics | Never Vaccinated | Received at least One Dose | Standardized Differencee |
|---|---|---|---|
| Individuals, n | 2403 | 11,356 | |
| Age group (years), n (%) | |||
| 18–39 | 209 (9) | 606 (5) | 0.13 |
| 40–69 | 1282 (53) | 5438 (48) | 0.11 |
| ≥70 | 912 (38) | 5312 (47) | 0.18 |
| Age (years), median (IQR) | 64 (53–74) | 68 (58–77) | |
| Women, n % | 953 (40) | 4484 (40) | 0 |
| Ethnicity, n (%) | |||
| Asian | 161 (7) | 933 (8) | 0.06 |
| Black | 269 (11) | 686 (6) | 0.18 |
| White | 1346 (56) | 6758 (60) | 0.07 |
| Indian Subcontinenta | 189 (8) | 1102 (10) | 0.06 |
| Other non-White | 340 (14) | 1502 (13) | 0.03 |
| Unknown | 98 (4) | 375 (3) | 0.04 |
| Comorbidity, n (%) | |||
| Diabetes | 1253 (52) | 5750 (51) | 0.03 |
| Cardiac disease | 824 (34) | 3513 (31) | 0.07 |
| Cancer | 193 (8) | 879 (8) | 0.01 |
| CCI, mean (SD)b | 4.3 (2.2) | 4.1 (2) | 0.1 |
| Years on dialysis, median (IQR) | 1.8 (0.3–4.4) | 2 (0.6–4.4) | 0.01 |
| Home dialysis,c n (%) | 589 (25) | 2848 (25) | 0.01 |
| Long-term care, n (%) | 99 (4) | 436 (4) | 0.01 |
| Public health unit regions, n (%) | |||
| Central East | 150 (6) | 817 (7) | 0.04 |
| Central West | 423 (18) | 1979 (17) | 0.01 |
| Durham | 96 (4) | 582 (5) | 0.05 |
| Eastern | 157 (7) | 765 (7) | 0.01 |
| North | 203 (8) | 904 (8) | 0.02 |
| Ottawa | 118 (5) | 650 (6) | 0.04 |
| Peel | 333 (14) | 1223 (11) | 0.09 |
| Southwest | 260 (11) | 1073 (9) | 0.05 |
| Toronto | 536 (22) | 2578 (23) | 0.01 |
| York | 122 (5) | 773 (7) | 0.07 |
| Missing | 5 | 12 | |
| Income quintiles, n (%) | |||
| 1 (lowest) | 766 (32) | 3158 (28) | 0.09 |
| 2 | 515 (21) | 2517 (22) | 0.02 |
| 3 | 463 (19) | 2120 (19) | 0.02 |
| 4 | 345 (14) | 1969 (17) | 0.08 |
| 5 (highest) | 304 (13) | 1548 (14) | 0.03 |
| Missing | 10 | 44 | |
| Economic dependency index,d n (%) | |||
| 1 (least marginalized) | 375 (16) | 1983 (18) | 0.05 |
| 2 | 466 (19) | 2003 (18) | 0.05 |
| 3 | 421 (18) | 2146 (19) | 0.04 |
| 4 | 541 (23) | 2372 (21) | 0.04 |
| 5 (most marginalized) | 578 (24) | 2780 (25) | 0.01 |
| Missing | 22 | 72 | |
| Previous PCR tests, n (%) | |||
| 0 | 483 (20) | 2555 (22) | 0.06 |
| 1 | 627 (26) | 2953 (26) | 0 |
| 2 | 455 (19) | 2136 (19) | 0 |
| ≥3 | 838 (35) | 3712 (33) | 0.05 |
Vaccine status was defined as of June 30, 2021. CCI, Charlson Comorbidity Index; IQR, interquartile range.
Includes Pacific Islander, Aboriginal, Middle Eastern/Arabian, Latin American, and other/multiracial. These categories are based on the classification scheme of the Canadian Organ Replacement Registry and the Ontario Renal Reporting System.
CCI includes include chronic respiratory diseases, chronic heart diseases, hypertension, diabetes, immunocompromising conditions due to underlying diseases or therapy, autoimmune diseases, CKD, advanced liver disease, dementia/frailty, and history of stroke or transient ischemic attack.
Home hemodialysis and home peritoneal dialysis.
Economic dependency is one of four indexes in the Canadian Index of Multiple Deprivation and relates to reliance on the workforce, or a dependence on sources of income other than employment income. https://www150.statcan.gc.ca/n1/en/catalogue/45200001.
Bold indicates differences between groups.