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(A) Life cycle of SARS-CoV-2. The key steps are highlighted, and drugs that were proposed to inhibit those steps are indicated where appropriate. (B) Pathophysiology of COVID-19. In most cases, viral infection is limited to the URT, and the patient recovers within 14 days with no further complications. However, the viral infection can migrate to the LRT and lead to ARDS or a cytokine storm. This has been proposed as the main cause of death from COVID-19-related complications.
