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The metabolite of Molnupiravir, NHC (represented in green) is a primary mimetic for cytidine, pairing with guanidine during viral replication. Tautomerism of NHC can allow it to occasionally mimic uridine, thus pairing with adenosine. When the NHC-containing strand is used as a template for further replication, adenosine or guanidine may be paired with NHC, thereby inducing mutagenesis.
